Parenchyma-Sparing Liver Resection
- incisionary
- Nov 24, 2025
- 3 min read

In recent years, a new, transformative approach for performing liver-related surgeries: Parenchyma-Sparing Liver Resection (PSLR). This approach is able to effectively remove tumors while also minimizing the loss of healthy liver tissue during the procedure. The PSLR technique is a type of hepatobiliary (liver-related) surgery, and unlike older, traditional methods of hepatobiliary surgeries, it prioritizes the long-term health of the liver while also being highly precise and efficient.
The primary goal of the PSLR technique is to maximize the amount of healthy liver tissue saved after the procedure. However, in order to do this, the surgical team must take many steps before the surgery to ensure that it is performed correctly. For instance, the medical team needs to take CT and MRI scans of the patient’s body to help identify the tumor that needs to be removed and visualize the area before starting the surgery. After conducting these scans, the surgeons will further analyze the tumor area by using technology to create a 3-D construction of the patient’s liver. After these steps, a team of medical professionals will then review the patient’s scans to help determine the best approach for removing the tumor. The PSLR offers many benefits for patients. It decreases the risk of medical complications after surgery, reducing hospital stays and shortening recovery time. Additionally, it reduces the risk of liver failure in the patient since it preserves more liver tissue compared to standard hepatobiliary procedures. In some cases, it may also reduce blood loss.
Despite the many benefits of PSLS, there are still a few notable disadvantages associated with this procedure. For instance, while it does decrease the overall risk of complications, it may actually increase the risk of certain complications (ex. Bile leaks). Additionally, since the surgeon has to meticulously navigate through the tissue to preserve as much of the liver’s tissue as possible, the procedure can be lengthy and require longer operating times. It can also be difficult to perform in certain areas. Furthermore, it is important to consider that since this procedure is relatively new, it may be difficult to draw definitive conclusions.
Overall, PSLS offers a promising new method for liver surgery, effectively removing tumors while also preserving the healthy tissue in the liver. PSLS offers many benefits to patients, especially those battling cancer. However, it still has its drawbacks, such as longer operating times and the potential for specific complications. It is important to weigh both the advantages and disadvantages of this procedure.
by Hawi Teju at Incisionary
APA References
Aghayan, D. L., Egidijus Pelanis, Åsmund Avdem Fretland, Kazaryan, A. M., Sahakyan, M. A., Røsok, B. I., Leonid Barkhatov, Bjørn Atle Bjørnbeth, Elle, O. J., & Edwin, B. (2017). Laparoscopic parenchyma-sparing liver resection for colorectal metastases. Radiology and Oncology, 52(1), 36–41. https://doi.org/10.1515/raon-2017-0046
Aghayan, D. L., Pelanis, E., Avdem Fretland, Å., Kazaryan, A. M., Sahakyan, M. A., Røsok, B. I., Barkhatov, L., Bjørnbeth, B. A., Jakob Elle, O., & Edwin, B. (2017). Laparoscopic parenchyma-sparing liver resection for colorectal metastases. Radiology and Oncology, 52(1), 36–41. https://doi.org/10.1515/raon-2017-0046
Burlaka, A. A., & Kolesnik, O. O. (2020). Parenchyma sparing multicomponent liver resection strategy for multiple bilobar synchronous colorectal cancer metastasis. Clinical Case Reports, 8(4), 661–666. https://doi.org/10.1002/ccr3.2742
Kalil, J. A., Poirier, J., Becker, B., Dam, R. V., Keutgen, X., & Schadde, E. (2019). Laparoscopic Parenchymal-Sparing Hepatectomy: the New Maximally Minimal Invasive Surgery of the Liver—a Systematic Review and Meta-Analysis. Journal of Gastrointestinal Surgery, 23(4), 860–869. https://doi.org/10.1007/s11605-019-04128-w



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