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The Role of Surgical Pathology in Trauma-Related Deaths


Regardless of age or socioeconomic status, trauma continues to be one of the world's leading causes of death. Trauma, whether from falls, assaults, traffic accidents, or work-related injuries, frequently results in unexpected and abrupt deaths. Though not all patients survive, advancements in trauma surgery, like the ATLS, have saved countless lives. When a patient dies after treatment, the crucial question is: was it the injury itself, or was something amiss during surgery? At its core, surgical pathology is the study of tissues removed during surgery or autopsy.  It goes beyond describing injuries when it comes to trauma-related deaths. It provides microscopic confirmation of tissue responses, timing of lesions, and complications that may not be evident to the naked eye. This level of detail often becomes critical when trying to distinguish between immediate and delayed causes of death.


One of the main jobs of surgical pathology is to identify the exact cause of death. Large injuries, such as a skull fracture or major bleeding, can often be seen during an autopsy. However, some fatal injuries are less obvious and only show up under a microscope. These include brain injuries like diffuse axonal injury, small fat clots in the lungs, or bruising of the heart muscle. For example, in a car accident, a person may look badly bruised on the outside, but microscopic study may reveal that the true cause of death was a torn blood vessel or hidden brain damage. This level of detail makes sure that the real reason for death is not missed or guessed.


Surgical pathology is also essential in cases where a patient survives the initial trauma but later dies in the hospital. In such situations, the cause of death may be related to medical complications, not just the injury itself. Common examples include infections, pneumonia, blood clots, or sepsis. By examining tissues, pathologists can confirm whether death was caused directly by the trauma or by later problems linked to treatment and recovery. This information helps doctors and hospitals understand what went wrong and how patient care can be improved.


Another important role of surgical pathology is to figure out when injuries happened. Tissues change over time after an injury. For instance, swelling and bleeding appear right away, while inflammation, tissue repair, and scar formation take hours or days to develop. By looking at these changes, pathologists can estimate the timing of an injury. This can be especially important in legal cases, such as when deciding if an injury happened during the fatal event, during earlier accidents, or even during attempts at resuscitation.


Surgical pathology also helps the justice system. Courts often need clear medical evidence when looking at deaths caused by accidents, workplace injuries, or possible crimes. The findings from pathology provide unbiased scientific facts that can support or challenge legal arguments. Families of the deceased can also benefit, since knowing the exact cause of death can give them closure. On a larger scale, information from trauma autopsies helps public health programs by showing patterns in injuries. These findings can guide prevention measures, improve safety standards, and reduce deaths from future accidents.


Written by Shanisse Tan at Incisionary


References


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World Health Organization. (2021). Injuries and violence: The facts 2021. WHO. https://www.who.int/publications/i/item/9789240047136 


Euler, S.A., Kastenberger, T., Attal, R. et al. Do we still need autopsy in times of modern multislice computed tomography?—Missed diagnoses in the emergency room. Arch Orthop Trauma Surg 137, 43–47 (2017). https://doi.org/10.1007/s00402-016-2588-4


Pfeifer, R., & Pape, H. C. (2008). Missed injuries in trauma patients: A literature review. Patient safety in surgery, 2, 20. https://doi.org/10.1186/1754-9493-2-20


Rippey, J. J., & Chatgidakis, C. J. (1975). The role of the autopsy in modern medical practice. A review. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 49(16), 662–664. https://pubmed.ncbi.nlm.nih.gov/1094563/


Miller, Catherine R. MD∗,†; Johnston, Robert D. DO; Blake, Brooke H. MD§; Aronson, Judith F. MD. The Role of Autopsy in Quality Assurance: Pilot Study of a Method for Prospective Reporting of Diagnostic Errors Discovered at Autopsy. The American Journal of Forensic Medicine and Pathology 44(3):p 166-172, September 2023. | DOI: 10.1097/PAF.0000000000000857 


Shojania, K. G., Burton, E. C., McDonald, K. M., & Goldman, L. (2003). Changes in rates of autopsy-detected diagnostic errors over time: a systematic review. JAMA, 289(21), 2849–2856. https://doi.org/10.1001/jama.289.21.2849 

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